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Recently, the U.S. pop star Michael? Jackson passed away in Los Angeles, heart attack, aged 50. One of his close friend, said in an interview, Michael? Jackson's heart most likely caused by drug abuse. According to domestic and foreign medical workers study found that use appropriate factors of sudden death is increasing, that is used for heart drugs such as digoxin, cedilanid (lanatoside), digitalis glycosides and toxic Mao Xuan Hanako drug digitalis glycosides of k, etc., this is the treatment of heart failure drugs, but if you use excessive, may induce arrhythmia, atrioventricular block and congestive heart failure, if not in time, can be due to ventricular fibrillation may cause death. Then there are those drugs may cause sudden death heart attack do? Drugs acting on the heart: the majority can lead to sudden cardiac death of the drugs fall into this category. Drug digitalis, digoxin. Now tend to low-dose treatment, excessive use or be used if the other can increase digoxin blood concentration of drugs, can occur "digitalis poisoning" and then delayed medical treatment because of ventricular fibrillation and death. Anti-arrhythmic drugs can be divided into four categories, improper use will lead to arrhythmia, such as quinidine important drug for treating arrhythmia, but when high drug concentration in the blood occurs when ventricular Array onset tachycardia, or ventricular fibrillation. Atrial fibrillation patients treated with the drug may induce atrial thrombus off, causing cerebral embolism or myocardial infarction and sudden death, a phenomenon known as "quinidine syncope." Lidocaine, phenytoin for the treatment of arrhythmia, if excessive or intravenous medication too fast can cause decreased blood pressure, or cardiac arrest, severe cases, death because of circulatory failure. In addition, some drugs used simultaneously is also the risk of cardiac arrest, such as Propranolol and verapamil, can cause cardiac arrest. Effect on the sympathetic, parasympathetic nervous system drugs such as dopamine, epinephrine and other drugs can cause excessive sympathetic or vagus nerve excitability, leading to the heart of self-regulation of excitability change. The recently held International Conference on Pharmacoepidemiology, a report that the use of large doses of rofecoxib (> 25mg) of the patients, the incidence of myocardial infarction and sudden cardiac death risk is seldom used nonsteroidal anti-inflammatory drugs the patient 3.15 times. Asthma drugs: aminophylline is effective in relief of asthma, chronic bronchitis, asthmatic symptoms, medication, application of excessive or for rapid intravenous injection, can lead to sinus tachycardia, respiratory distress who may cause ventricular fibrillation. Therefore, arrhythmias associated with chronic obstructive pulmonary disease patients, aminophylline should be used with caution. There are also widely used in asthma aerosol isoproterenol people, the drug easily available, because of the role of time is only about 1 hour, so patients often require repeated several applications, but if the over-application can cause ectopic ventricular heart rate, and even lead to ventricular fibrillation and sudden death, so patients with coronary heart disease and hyperthyroidism use with caution. Antimalarial drugs: chloroquine and chloroquine phosphate is an effective anti-malarial drugs, quinidine-like effect of similar, high-dose application can cause bradycardia, arrhythmia, hypotension, and even cause acute cardiogenic cerebral short Oxygen syndrome, resulting in deaths. Patients with atrial fibrillation with quinidine treatment, if used improperly, can induce atrial thrombus off, causing cerebral embolism or myocardial infarction and sudden death. In addition, a large number of episodes of malaria drugs, can occur leading to irreversible shock and death. So the drug on the elderly and patients with structural heart disease contraindications. Chlorpromazine drugs: This is the treatment of mental illness in a class of drugs, including chlorpromazine, perphenazine, fluphenazine and so on. Such drugs can cause severe orthostatic hypotension, paralytic ileus, and thromboembolic disease, easy to cause sudden death. Antidepressant drugs: In addition to anti-depressants such as imipramine things, can lower blood pressure, prone to cause arrhythmia. Recently proved that it has quinidine-like cardiac effects, so caution. Potassium, calcium and other drugs added electrolytes: electrolyte is to maintain an essential component of cardiac physiological function, blood concentration is too high or too low will cause cardiac arrest.

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